VISDB Viral Integration Site DataBase

VIS ID

TVIS10013952

Fusion event

HBV-IMMP2L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1989

Orient

+

Integrated sequence

GTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGAT| |CTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGG

Chromosome

chr7

Cytoband

q31.1

Reference genome

Start

End

110503366/110863310 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-587 ; hsa-mir-3180-5p ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-6815-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-103a-2-5p ; hsa-mir-3188 ; hsa-mir-770-5p ; hsa-mir-4712-5p

Nearest miRNA

hsa-mir-10525/Upstream/8391779; hsa-mir-10399/Downstream/3790035;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/2292848, chr7-CpG: 68/Downstream/698713

Upstream sequence

GTTATGGTCCCACAGATTAGCCTCAATTGTTTTGAATTCATcagtaattgtcaaacttgattgcgcattagagttaccttgggaactttgaaaaatgttg

Downstream sequence

gatccaggttaaaagagcagcccccactgggacatgtttgttctcatgacacaaagaaaagagcaatggaaagtccacagtatgatttttcaacattttt