VISDB Viral Integration Site DataBase

VIS ID

TVIS10013985

Fusion event

HBV-FNIP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1073

Orient

-

Integrated sequence

TATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGT| |ATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTC

Chromosome

chr5

Cytoband

q31.1

Reference genome

Start

End

131102635/131766942 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-18a-3p ; hsa-mir-30d-5p ; hsa-mir-92a-3p ; hsa-let-7a-5p ; hsa-mir-136-5p ; hsa-mir-379-3p ; hsa-mir-493-5p ; hsa-mir-382-5p ; hsa-mir-218-5p ; hsa-mir-223-5p ; hsa-mir-4719 ; hsa-mir-511-3p ; hsa-mir-489-3p ; hsa-mir-137 ; hsa-mir-363-3p ; hsa-mir-92b-3p ; hsa-mir-367-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-5096 ; hsa-mir-5687 ; hsa-mir-627-3p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4773 ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-23c ; hsa-mir-6516-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-455-3p ; hsa-mir-203b-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6499-3p ; hsa-mir-767-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6087 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-4459

Nearest miRNA

hsa-mir-10397/Upstream/2369795; hsa-mir-103a-1/Downstream/450907;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/131130, chr5-CpG: 127/Downstream/29294

Upstream sequence

gtcattagatccagtaacaagaagtttctatgcctacagagcaggtagggacaatggcccttgttcagcatgaaacagttatagaggacaccctctcatc

Downstream sequence

tgcactccgtccacagactcccacaccaaatctcctcgggaaacactcttcacagacacactcagaaacaatgctcttccaatttccaggtattccataa