VISDB Viral Integration Site DataBase

VIS ID

TVIS10014000

Fusion event

HBV-ARHGEF17 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1740

Orient

-

Integrated sequence

TGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGA| |GTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAA

Chromosome

chr11

Cytoband

q13.4

Reference genome

Start

End

73066252/73355207 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-452-3p ; hsa-mir-4666a-5p ; hsa-mir-4320 ; hsa-mir-4708-3p ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-7153-3p ; hsa-mir-361-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-6834-3p

Nearest miRNA

hsa-mir-10392/Upstream/571615; hsa-let-7a-2/Downstream/1044030;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/11950, chr11-CpG: 66/Downstream/6866

Upstream sequence

ctggtggggggatctgcataagcaaaggccaaatggctagaatgagtctgtgtcactcagagaatggggaaagggagacctgcctggctggacttcgtga

Downstream sequence

gggtggaggtctagggatggaaatgcccagttggaagtgagagaaccaggTCTGAGCTCACAGGATACATTCAGGTCTACATATGTGCATACATGAACAG