VISDB Viral Integration Site DataBase

VIS ID

TVIS10014004

Fusion event

HBV-FAIM2 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1263

Orient

-

Integrated sequence

CGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGC| |CGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATA

Chromosome

chr12

Cytoband

q13.12

Reference genome

Start

End

50261607/49867824 (Hg38)

Orient

-

Location type

UTR3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-3152-5p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-6836-3p ; hsa-mir-1299 ; hsa-mir-7977 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-3655 ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-4267

Nearest miRNA

hsa-mir-1244-3/Upstream/1095787; hsa-let-7i/Downstream/366318;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/24632, chr12-CpG: 48/Downstream/35973

Upstream sequence

CTTGTGACACCTGCTCAGCTGCGGTTTCCTTAATCTTGCATTCCTGTTCCCCTGCCCTTCCTACTTCTGACGCCTCTCCTGGTGTTTCAGGATTCCTCAC

Downstream sequence

TGCCTGGATTGGAGATGGAACGCATAGACTTTGGCCCTGACCCTGCTGCCTACACTGTGGTACCTGCCACCCCCCCTCAGGACCCAGAGTAGGAGGCTGC