Fusion event
HBV-GPC6 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
CATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTG| |GAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGC
End
93964290/93312037 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1297/Upstream/821817; hsa-mir-1267/Downstream/3115192;
Upstream sequence
ATGGGAGGTAAAAAAGAAAGAAGCTAAAGAGAAAATGCACACCTTAACAGAATAACTCAAAAAAGTTATGGAGAGTTATGTGAGTAATAAACAACTCATT
Downstream sequence
AGGAAAGTTACTTTGGCTTAGAAAGTACATAAGCAGCCTAATTATGTAGTCATTTCACATCTATCTTATGTGAAATTGGCAGTACCAAACAAACAGCTTC
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.