SH3RF3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014029
Fusion event
HBV-SH3RF3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
868
Orient
-
Integrated sequence
CTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTC| |TCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAAC
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
109816115/109199659 (Hg38)
End
109816115/109199659 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
SH3RF3
Nearest miRNA
hsa-mir-1285-2/Upstream/58071; hsa-mir-10b/Downstream/113912;
Nearest TSS
ENST00000437798/Upstream/70311; ENST00000356454/Downstream/368194;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/69282, chr2-CpG: 246/Downstream/413670
Upstream sequence
aatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatgg
Downstream sequence
aatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatgg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate