VISDB Viral Integration Site DataBase

VIS ID

TVIS10014036

Fusion event

HBV-chr2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

887

Orient

-

Integrated sequence

CCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTAT| |GTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAG

Chromosome

chr2

Cytoband

q24.2

Reference genome

Start

End

160626657/159770146 (Hg38)

Orient

+

Location type

UTR3

Target gene

CD302 ; LY75-CD302

miRNAs that regulate target gene

hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-16-2-3p ; hsa-mir-16-2-3p ; hsa-mir-195-3p ; hsa-mir-195-3p ; hsa-mir-3672 ; hsa-mir-3672 ; hsa-mir-4690-3p ; hsa-mir-4690-3p ; hsa-mir-4786-5p ; hsa-mir-4786-5p ; hsa-mir-5583-3p ; hsa-mir-5583-3p ; hsa-mir-5685 ; hsa-mir-5685 ; hsa-mir-6864-3p ; hsa-mir-6864-3p ; hsa-mir-769-5p ; hsa-mir-769-5p

Nearest miRNA

hsa-mir-128-1/Upstream/583245; hsa-mir-10b/Downstream/637664;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/56978, chr2-CpG: 69/Downstream/27572

Upstream sequence

CTTAATCACTTTCCTACCCAAATTCTACCACTCCTTTAAGAACTCCTTTAGAACTCTTTTAGTTCACATAATACGCCATATTTTTTTTACTGTGCCTGTA

Downstream sequence

GTTCTTCAAGGAGTGGTACAATTTGGGTAGGAAAACCAGGCAGGAATTCCAGGGTAGTGTTCAATATTGACATTAGTAATAGTCTATCAATAATAAAATA