Basic Information
VIS ID
TVIS10014069
Fusion event
HBV-chr8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
301
Orient
+
Integrated sequence
CAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTC| |TTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCAT
Host Sequence
Chromosome
chr8
Cytoband
q11.21
Reference genome
End
51787482/50874922 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/7978647; hsa-mir-10400/Downstream/10839866;
Nearby gene
SNTG1(-82055) ; PXDNL(+444655) ;
Upstream sequence
ATGTGGCTacttgatctcacagcagttccctgtgacaagtaaaattgctcctgttggatgaggacactgaggctgaggaggagggagtgagaggatgaag
Downstream sequence
acctgaccattgcaagaaaaagaaacaaacagaaagcaacaacaacagcatcaacaaaaaaagttcccacaaaaaccccatccaagggtcaaaggtgggt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate