VISDB Viral Integration Site DataBase

VIS ID

TVIS10014075

Fusion event

HBV-TMEM167B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1762

Orient

-

Integrated sequence

GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA| |AAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTAC

Chromosome

chr1

Cytoband

p13.3

Reference genome

Start

End

109636863/109094241 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-365a-3p ; hsa-mir-4635 ; hsa-mir-5586-3p ; hsa-mir-1264

Nearest miRNA

hsa-mir-101-1/Upstream/1196937; hsa-mir-11399/Downstream/504652;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/3231, chr1-CpG: 74/Downstream/5800

Upstream sequence

tggtggcaggcgcctgtaatctcagctactcaagaggctgaggcaggagaattgcttgaacccgggtggcagaggttgcagtgagccgagatcgcgccac

Downstream sequence

tgcactccagcctggccgacagagtgagactgcctccaaaaataaaataaaaaCATCCCAGGCCCTTGAGAGCGTTGATATGTCTGTCTGTGACTAGAGA