VISDB Viral Integration Site DataBase

VIS ID

TVIS10014094

Fusion event

HBV-ANO3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1785

Orient

-

Integrated sequence

CAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTG| |TAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCC

Chromosome

chr11

Cytoband

p14.2

Reference genome

Start

End

26301254/26279707 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-18a-3p ; hsa-mir-186-5p ; hsa-mir-26a-5p

Nearest miRNA

hsa-mir-210/Upstream/2860517; hsa-let-7a-2/Downstream/1235263;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/1782515, chr11-CpG: 29/Downstream/52283

Nearby gene

LUZP2(-1197068) ; ANO3(+52424) ;

Upstream sequence

gcacatttctgtgagctctgtttcaagtcaaatcaagatagccttgcaagtagggtcttcagggacttgcaagtggggtctcccagggaaccagaaaact

Downstream sequence

ggataaatagtgacaactgggagtgaggctttaaaggggccccaatctcattctgtgtccatccggcaacttcaagactccttatttccactgtgattgt