Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014102
Fusion event
HBV-CRY1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1790
Orient
-
Integrated sequence
ACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGC| |ATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGG
Host Sequence
Chromosome
chr12
Cytoband
q23.3
Reference genome
End
107416265/107022487 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7i/Upstream/2430771; hsa-mir-1178/Downstream/1613323;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/35189, chr12-CpG: 121/Downstream/70347
Upstream sequence
AAAATACTGAATAAAATCACTAATTTTCATTAAATAAAAGTGACTATTAGCAAAAATTTAATTTGTGAACATAAAAACATACAAAGAAGTATCAAAGCAA
Downstream sequence
TTAAATTGGTTTCATTGTTTAAACTTGATGAAATATTTTCTGTATGAAAATGGCTTTTCATATAGAAAGGAAAACTTGAAAAATCTAGAATATCTTCTGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.