CRY1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014103
Fusion event
HBV-CRY1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
1952
Orient
+
Integrated sequence
CATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTC| |GTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCT
Host Sequence
Chromosome
chr12
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
107448050/107054272 (Hg38)
End
107448050/107054272 (Hg38)
Orient
+
Location type
Intronic
Target gene
CRY1
miRNAs that regulate target gene
hsa-mir-324-5p
Nearest miRNA
hsa-let-7i/Upstream/2462556; hsa-mir-1178/Downstream/1581538;
Nearest TSS
ENST00000382841/Upstream/3913; ENST00000547679/Downstream/39026;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/66974, chr12-CpG: 121/Downstream/38562
Upstream sequence
aaaaacagagaaatgaccagaattagaatatataaatcagaagaaaggtaattagagtttgcgtttcaagggccttgaattatctaataaatagacaaaa
Downstream sequence
ttattgattaactttagacattaaccaatgtgcttctggtaatttctagagtaaacactaaaagaatagctaaaataatgtgtaattattttattaatta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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