Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014106
Fusion event
HBV-HSD17B6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1823
Orient
-
Integrated sequence
TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
Start
End
57176429/56782645 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/2445331; hsa-let-7i/Downstream/411859;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/30096, chr12-CpG: 79/Downstream/223439
Upstream sequence
aattgtgtgatcatcatggttcattgcagcctcaacctcctgggctcaaacgatccttccacctcaacttccctggtagctgggactatgggtgcacgct
Downstream sequence
gccatgcccagctaattttttttttttttttttttattgatcattcttgggtgtttctcgcagagggggatttggcagggtcataggacactagtggggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.