Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014107
Fusion event
HBV-HSD17B6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2606
Orient
+
Integrated sequence
GTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCA| |CAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTA
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
Start
End
57176491/56782707 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/2445393; hsa-let-7i/Downstream/411797;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/30158, chr12-CpG: 79/Downstream/223377
Upstream sequence
ctcaacttccctggtagctgggactatgggtgcacgctgccatgcccagctaattttttttttttttttttttattgatcattcttgggtgtttctcgca
Downstream sequence
gagggggatttggcagggtcataggacactagtggggggaaggtcagcagacaaacaagtgaacaaaggtctctggttttcctaggcagagtgtttgtgt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.