CCL17 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014122
Fusion event
HBV-CCL17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1811
Orient
-
Integrated sequence
AAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
57444567/57410655 (Hg38)
End
57444567/57410655 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCL17
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-128-3p
Nearest miRNA
hsa-mir-1225/Upstream/506302; hsa-mir-11401/Downstream/361634;
Nearest TSS
ENST00000527434/Upstream/5888; ENST00000616880/Downstream/3214;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/28229, chr16-CpG: 69/Downstream/36428
Upstream sequence
TTCCTGATTGCCCTGACAGACCTCCAGGTCCTAGAATCCTCACAGCAGCATAAAGATCTCTCAAGATGCTTCTCACAGGCCCAGACTTCAGAATAGTTTG
Downstream sequence
TCTGGAAGTTCCCTTGGCATCCATCCCATAGCCTGGGAGAACTGAGGAGGGATAAACTCGGTTAATCCCTGGAGAGGAAACCACCTCAAAAATGTCCCTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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