Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014135
Fusion event
HBV-GPR39 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1767
Orient
-
Integrated sequence
TTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGT| |CTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTC
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
End
133342458/132584885 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/151065; hsa-mir-10b/Downstream/1542240;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/167014, chr2-CpG: 27/Downstream/656
Upstream sequence
TTAGACGATTACCAGTGTTCGCTCCCCCAAACTGGAATAAGCCTCTTGATTTGTCTGCATTCATTTGGATAACCTACAAAATCTTGTTTATGGACTTTTA
Downstream sequence
ACAGTGAGAGAGAGCATTTCTGGAGACACTGATTTCCACAGATCTCAGAACCTCCTCAAAAACCTGAGCACGGGGGAAGGGGAGGCCATGGGCTCTCCTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.