VISDB Viral Integration Site DataBase

VIS ID

TVIS10014137

Fusion event

HBV-SGO2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2788

Orient

+

Integrated sequence

GGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGA| |GAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTC

Chromosome

chr2

Cytoband

q33.1

Reference genome

Start

End

201446174/200581451 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-335-3p ; hsa-mir-3613-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-10b/Upstream/11448340; hsa-mir-1244-1/Downstream/6201783;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/54957, chr2-CpG: 47/Downstream/4352

Upstream sequence

ctcctgtagtttttgcttcagaagggtggttgctctgctttttgctatgtaaatatcatgattattacttattcattttggattatggcctttattatat

Downstream sequence

taaaaatgtcctcatttgtcATGTTCAGTGCTCTGGACTAAAGACTTAAAGTCTTTAAGATATAAAGACTTTAAAAACATATTTATGAGACCTTCCTGAT