VISDB Viral Integration Site DataBase

VIS ID

TVIS10014138

Fusion event

HBV-ACADL integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2450

Orient

+

Integrated sequence

GACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATG| |TTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAA

Chromosome

chr2

Cytoband

q34

Reference genome

Start

End

211065807/210201083 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-7106-5p ; hsa-mir-149-3p ; hsa-mir-6134 ; hsa-mir-6089 ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-34b-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4279 ; hsa-mir-7111-3p ; hsa-mir-642a-5p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-2276-5p ; hsa-mir-6892-3p

Nearest miRNA

hsa-mir-10b/Upstream/2446202; hsa-mir-1244-1/Downstream/2225180;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/29170, chr2-CpG: 85/Downstream/23606

Upstream sequence

aaaccctgccttcaagcctaaacagcctaaaggctgaaaaacccgactgctggtcccagatgaagcctgccctttcccaactgatcctttctgaataatg

Downstream sequence

cccacctgtgcactgggaggacggggtggagcctcgggaagttcacactgtttgcagaggagaggagcctagcctctcctgttcctgtgtgatgacctag