VISDB Viral Integration Site DataBase

VIS ID

TVIS10014140

Fusion event

HBV-ABCA12 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1503

Orient

-

Integrated sequence

ATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTC| |TGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCA

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

215831951/214967227 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1249-3p ; hsa-mir-3679-3p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-6730-3p ; hsa-mir-4287 ; hsa-mir-4685-3p ; hsa-mir-6734-3p ; hsa-mir-5088-3p ; hsa-mir-6887-3p ; hsa-mir-660-5p ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-329-3p ; hsa-mir-362-3p

Nearest miRNA

hsa-mir-10b/Upstream/1209068; hsa-mir-1244-1/Downstream/2933286;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/156899, chr2-CpG: 62/Downstream/344599

Upstream sequence

ATTTCCAATTTAGAAACAGGCAGAAATTGGGAAGAGAGTTGTTCTGTGGATAGCACTAAATTATTAGTTATTCAGGATCTCTTCTAGGCAAAGCTTGAAA

Downstream sequence

TAAACTGGAGAAATCATTATCTACATCCCTGTGGCAGATCCATGGGATTctgagactagaactaaggtatcctggctgccaatAATGGTAATAAAAACTA