Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014147
Fusion event
HBV-DNAH6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
3212
Orient
-
Integrated sequence
CCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG| |
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
Start
End
84936199/84709075 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/4842492; hsa-mir-10b/Downstream/1074525;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/192514, chr2-CpG: 77/Downstream/171532
Upstream sequence
acaccctcagtcattgtgataacccgaaacttctccatatgctttcagactctcccaacagggaaaatacaaacctggttgaaaaccactgCGAcaaccc
Downstream sequence
agtcatttacacatgagacaactgaggtccaaatagagggaatgatgtttccaaagtcacatctaactaatggtatagtcagagtacctaggcctcctga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.