Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014157
Fusion event
HBV-KLF15 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2801
Orient
+
Integrated sequence
TATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATA| |GCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACC
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
End
126063978/126345135 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/554583; hsa-mir-12124/Downstream/1230131;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1216, chr3-CpG: 196/Downstream/10805
Upstream sequence
agagattctggtatgtggtgtctttgttctcgttggtttcaaagaacatctttatttctgccttcatttcgttatttacccagtagtcattcaggagcag
Downstream sequence
ccttagagctcagctcgaatgtcacttccttaggaaatccctccaggactgcatccaattctaggctcctgtggcattacacacctctctctcctcattc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.