VISDB Viral Integration Site DataBase

VIS ID

TVIS10014165

Fusion event

HBV-SFMBT1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1767

Orient

-

Integrated sequence

TTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGT| |CTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTC

Chromosome

chr3

Cytoband

p21.1

Reference genome

Start

End

52969244/52935228 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-let-7b-5p

Nearest miRNA

hsa-let-7g/Upstream/88676; hsa-mir-12124/Downstream/2917264;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/37404, chr3-CpG: 22/Downstream/63569

Upstream sequence

gcttccctgaggtctgatttaactttggtttggtattctatgatatctaacagttacagtctgatatctctttgttctcctctcctttccataggaaact

Downstream sequence

aatcctaagtgccctggcgtcaacaactgtcacctcatggccaatctgtttcatctaAACCAggatttacaagctacaactcgagggcttaatccagcct