VISDB Viral Integration Site DataBase

VIS ID

TVIS10014167

Fusion event

HBV-WDR17 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1762

Orient

-

Integrated sequence

GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA| |AAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTAC

Chromosome

chr4

Cytoband

q34.2

Reference genome

Start

End

177045951/176124800 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-190a-3p ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-4666a-5p ; hsa-mir-5011-5p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5680 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-8057 ; hsa-mir-6844 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-143-5p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-205-3p ; hsa-mir-466 ; hsa-mir-5580-3p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-3129-5p ; hsa-mir-3194-3p ; hsa-mir-323a-5p ; hsa-mir-431-5p ; hsa-mir-4695-3p ; hsa-mir-5691 ; hsa-mir-6787-3p ; hsa-mir-6805-3p

Nearest miRNA

hsa-mir-12113/Upstream/1700936; hsa-mir-1305/Downstream/6044493;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/58591, chr4-CpG: 34/Downstream/70592

Upstream sequence

tacagaactctccaccccaaatcaacagaatatacatttttttcagcaccacaccacacctattccaaaattgaccacatagttggaagtaaagctctcc

Downstream sequence

TATTGACAAGATCAGAGTATGTTATTTATCTGTATATTTTCTTACTGCTTTTCGGTAACAAATGGGAGACACATTCAAGGCACTGGAAATTGCCAAAACA