Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014170
Fusion event
HBV-RELL1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
797
Orient
+
Integrated sequence
AGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACC| |GCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGAT
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
Start
End
37641671/37640049 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/398058; hsa-mir-1243/Downstream/1227983;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/186093, chr4-CpG: 121/Downstream/45730
Upstream sequence
gcagatcacttgaggtcaggagttcaagaccagcctggctaacttggcaaaatcctgtctctactaaaaatacaaagaaattagccagatatagtggcat
Downstream sequence
gctttacatataagagagtgagtttttttttggccccgatccaatttttatcttcttaggggacacattgccccattgcaacccttgagaacatatgGGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.