VISDB Viral Integration Site DataBase

VIS ID

TVIS10014177

Fusion event

HBV-WDR70 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

557

Orient

+

Integrated sequence

AAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTA| |TCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCA

Chromosome

chr5

Cytoband

p13.2

Reference genome

Start

End

37529644/37529542 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6844 ; hsa-mir-6873-3p ; hsa-mir-9-5p ; hsa-mir-4778-3p ; hsa-mir-7152-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-660-3p ; hsa-mir-5193

Nearest miRNA

hsa-mir-10397/Upstream/1381554; hsa-mir-103a-1/Downstream/1027960;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/149988, chr5-CpG: 51/Downstream/305027

Upstream sequence

TGTAACTCCGTTATGCACAGATCAGTCATACCCAGAATGATAACACTGAAGTTTAACCATATTTCTGCTGGTCTCCTTTAATATTTCTTTACACTTACTT

Downstream sequence

gttaggtaaattcctaagtatttatttatttttttttgcagctattgtgaaagtggttgagttcttgatttgattctgagtgtggttgctattggtatat