Basic Information
VIS ID
TVIS10014178
Fusion event
HBV-chr5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1487
Orient
-
Integrated sequence
CTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCT| |CGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACT
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
End
38000028/37999926 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-10397/Upstream/1851938; hsa-mir-103a-1/Downstream/557576;
Nearby gene
GDNF(-160246) ; EGFLAM(+258483) ;
Upstream sequence
gccaactaattcttcctggttgtccaaaatgagtacagaatggcaattcccctaggaaattttctcctctgggagatgaagctattagcaaagcaagtca
Downstream sequence
ggcctgtgagctagtaatggtttattaaaattttaaatgtttaggggaaaaatcaaaaaaaagaataatactctgtgacatgtgaaaactatatgaaatt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate