VISDB Viral Integration Site DataBase

VIS ID

TVIS10014191

Fusion event

HBV-THSD7A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1765

Orient

-

Integrated sequence

TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT

Chromosome

chr7

Cytoband

p21.3

Reference genome

Start

End

11743562/11703935 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-448 ; hsa-mir-6867-5p ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-5011-5p ; hsa-mir-586 ; hsa-mir-1277-5p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-3119 ; hsa-mir-3158-3p ; hsa-mir-532-5p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-584-3p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-3692-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-153-5p ; hsa-mir-210-3p

Nearest miRNA

hsa-mir-339/Upstream/4636890; hsa-mir-10399/Downstream/6423285;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/729674, chr7-CpG: 25/Downstream/127846

Upstream sequence

ATATTTGCTTTCATAGAGTTTAGGATTTATAAGGAGAATAAGAATATTTTTTTAAAAAATGTTAAAAGTACAATACACAGTGGTGAAACACAAAAACACT

Downstream sequence

AATTGGGGTATAATTGGCAACAGACACAGACTTGAGTTGAAAACAAAATAGGTTTCAGAATACATTAGATTATCACTTAATTAGTGGTATCTTTGAAGCA