VISDB Viral Integration Site DataBase

VIS ID

TVIS10014193

Fusion event

HBV-ZPBP integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

217

Orient

-

Integrated sequence

TCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCT| |TGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCA

Chromosome

chr7

Cytoband

p12.2

Reference genome

Start

End

50129805/50090209 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-607 ; hsa-mir-2053 ; hsa-mir-4795-3p ; hsa-mir-3671 ; hsa-mir-889-3p ; hsa-mir-569 ; hsa-mir-205-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p

Nearest miRNA

hsa-mir-1183/Upstream/5208409; hsa-mir-10399/Downstream/6865576;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/314053, chr7-CpG: 42/Downstream/2767

Upstream sequence

TCTGTCCTCCAAAAGAGGCCAATTGGGCTGGCGAGGGACTGGAGATCCGTCTCCAGTGGAAAGGTGAAGATGGACTATGCTGGATGGAACAATCTCTGTG

Downstream sequence

aaacccaatttgtagtcttttatccctcacccccatcccaccgtttctcccacccccgagtccccaaagaccattgtatcattctcatgcctttgcatcc