Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014196
Fusion event
HBV-SGCZ integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1811
Orient
-
Integrated sequence
AAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
Start
End
14402626/14545117 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-124-1/Upstream/1817813; hsa-mir-10400/Downstream/308321;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1268326, chr8-CpG: 87/Downstream/691611
Upstream sequence
ttcctcctttctgggaagggcatccctgaaagaaaggcagcagccccagtcaggggcttatagataaaaactcccatttccctgggagagggcacctggg
Downstream sequence
cacttatggaaaatagaaagaacctacattgaaatattgggggcatgtcccccaataAACACTGACACAGACTGAAAACTAAATTTAATTTTCATAAATG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.