Basic Information
VIS ID
TVIS10014200
Fusion event
HBV-chr8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
1997
Orient
+
Integrated sequence
GGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGA| |TACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTA
Host Sequence
Chromosome
chr8
Cytoband
p11.1
Reference genome
End
43094801/43239658 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/343383; hsa-mir-10400/Downstream/18475130;
Nearby gene
HGSNAT(-36831) ; POTEA(+52784) ;
Upstream sequence
ACTTGAATATCTTCACCTTGAAACTCTTGGAAAACTGATTGAAATATGGCTCATAAGCAGAGTTCATCAGAATTAATTGAGAGTTAATTAAGAATAAGAA
Downstream sequence
tacataaaatatcaaagtacaccaaatacatattatatactgtacataaaatatcaaagtacaccaaatacatattatatactgttcataaaatatcaaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate