VISDB Viral Integration Site DataBase

VIS ID

TVIS10014203

Fusion event

HBV-LURAP1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1695

Orient

-

Integrated sequence

CCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGA| |CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA

Chromosome

chr9

Cytoband

p23

Reference genome

Start

End

12812755/12812756 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-503-5p ; hsa-mir-1253 ; hsa-mir-3185 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-5703 ; hsa-mir-7846-3p ; hsa-mir-1228-3p ; hsa-mir-646 ; hsa-mir-6882-5p ; hsa-mir-497-5p ; hsa-mir-16-5p ; hsa-mir-6838-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-424-5p ; hsa-mir-300 ; hsa-mir-381-3p

Nearest miRNA

hsa-mir-101-2/Upstream/6804852; hsa-let-7a-1/Downstream/5760550;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/36942, chr9-CpG: 144/Downstream/465557

Upstream sequence

cagagcaagactctgtctcagaaatgaacaaagaaagaaaaaGAGAGAGAGAgagggagggaaggaggaaggaaggaaggaaggaaggaaggaaggaaga

Downstream sequence

CTCTGCATTATAAAGCCTACTGTTTATAACAGTGGCCTCTTATTTTAGAAATATAGCCATCAAAAATTATTATAATACAAAAGCATAAATGTTCAACTGA