VISDB Viral Integration Site DataBase

VIS ID

TVIS10014206

Fusion event

HBV-VPS13A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

807

Orient

-

Integrated sequence

AGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCA| |ATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTC

Chromosome

chr9

Cytoband

q21.2

Reference genome

Start

End

79944918/77330002 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-15b-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4326 ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-138-2-3p

Nearest miRNA

hsa-mir-101-2/Upstream/6519918; hsa-let-7a-1/Downstream/6639746;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/151590, chr9-CpG: 108/Downstream/317528

Upstream sequence

ttgagcgatcctcctgcctcggcccccctagtagctgggattacaggcacgcaccaccatgcccagctaatgtttgtgtttttagtagagacagggtttt

Downstream sequence

ACGCTTCTGTTTCTTTCTTACCTTTGTAGtttttgagacacagggtcttgctctatcgcccaggagtgcagtggcatgatcagtgctcactgcaaccttg