VISDB Viral Integration Site DataBase

VIS ID

TVIS10014211

Fusion event

HBV-IL1RAPL1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1848

Orient

+

Integrated sequence

AGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCT| |TGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTAC

Chromosome

chrX

Cytoband

p21.2

Reference genome

Start

End

29574842/29556725 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-151a-5p ; hsa-mir-4307 ; hsa-mir-6768-5p ; hsa-mir-8485 ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6840-5p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-7108-5p ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-6867-5p ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-663b ; hsa-mir-5197-5p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-4279 ; hsa-mir-100-3p ; hsa-mir-539-5p

Nearest miRNA

hsa-mir-23c/Upstream/1061062; hsa-let-7f-2/Downstream/17553;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/1692670, chrX-CpG: 30/Downstream/690330

Upstream sequence

gcttcaagataaatgatgatatcttgggagaaccagattttagctgatgaaaaaatagtaatgaaaattagaaaCTAATTTTGTAAGAGGGTGAGAAAAA

Downstream sequence

ACTTTTTGAAAAGTGTAATAGGTTTGAGAAAAATGGCTTAATTTAAAATATGTATTTTCTATTATATGTGCATGATTTTTATGAAGATATATTCTCAGAA