Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014224
Fusion event
HBV-FANK1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
1
Orient
+
Integrated sequence
A| |ATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGAC
Host Sequence
Chromosome
chr10
Cytoband
q26.2
Reference genome
End
127636445/125947876 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-107/Upstream/128054; hsa-mir-202/Downstream/3895423;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/50907, chr10-CpG: 132/Downstream/439710
Upstream sequence
acagaactctccaccccaaatcaacagaatatacatttttttcagcagcacaccacacctattccaaaattgaccacatacttggaagtaaagctctcct
Downstream sequence
cagcaaatgtaaaagaacagaaattataacaaactatctctcagaccacagtgcaatcaaactagaactcaggattaagaatctcactcaaagccactca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.