VISDB Viral Integration Site DataBase

VIS ID

TVIS10014233

Fusion event

HBV-PRMT8 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

123

Orient

+

Integrated sequence

TCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCA| |ATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGA

Chromosome

chr12

Cytoband

p13.32

Reference genome

Start

End

3611589/3502423 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-330-3p ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-2276-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3939 ; hsa-mir-3925-5p

Nearest miRNA

hsa-mir-3649/Upstream/1842043; hsa-let-7i/Downstream/3461276;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/8581, chr12-CpG: 59/Downstream/250479

Upstream sequence

tcttgtaggcatttagtgctataaatttccctctacacactgctttgaatgcgtcccagagattctggtatgtggtgtctttgttctcgttggtttcaaa

Downstream sequence

gaacatctttatttctgccttcatttcgttatgtacccagtagtcattcaggagcaggttgttcagtttccatgtagttgagtggctttgagtgagattc