Basic Information
VIS ID
TVIS10014241
Fusion event
HBV-chr14 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
55
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATT| |TCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAA
Host Sequence
Chromosome
chr14
Cytoband
q31.2
Reference genome
End
84108197/83641853 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/6375563; hsa-mir-1185-1/Downstream/10306373;
Nearby gene
LINC00911(+1752026) ;
Upstream sequence
gatcaatgagacagaaagtcaacaaggatacccaggaattgaactcagctctgcatcaagccgacctaatagacatctacagaactctccacgccaaatc
Downstream sequence
aacagaatatacatttttttcagcaccacaccacacctattccaaaattgaccacatagtgggaagtaaagctctcctcagcaaatgtaaaagaacagaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate