Basic Information
VIS ID
TVIS10014252
Fusion event
HBV-chr18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1703
Orient
+
Integrated sequence
CGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGG| |CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
End
78016240/80258357 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/7404975;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/10569, None/Downstream
Nearby gene
PARD6G(-10843) ;
Upstream sequence
tgtcctcggtctcttgcctcggcaAAGATTAGAttagggttaggtgagggtgagggtgagggtgagggtgagggtgagggtgagggttagggttagggtg
Downstream sequence
agggtgagggtgagggtgagggtgagggtgagggtgagggttagggtgttagagggttagggttagggttagggttagggttagggggttagggggttag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate