hsa-mir-4761-5p _LIHC.png
NLRP11 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014255
Fusion event
HBV-NLRP11 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|middle S protein|
Start
2
Orient
+
Integrated sequence
AA| |TTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACT
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh37/hg19
Start
56336467/55825101 (Hg38)
End
56336467/55825101 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
NLRP11
miRNAs that regulate target gene
hsa-mir-377-3p ; hsa-mir-3671 ; hsa-mir-4761-5p ; hsa-mir-370-5p ; hsa-mir-8485 ; hsa-mir-3974 ; hsa-mir-4496 ; hsa-mir-1193
Nearest miRNA
hsa-let-7e/Upstream/436859; hsa-mir-10394/Downstream/2509587;
Nearest TSS
ENST00000633603/Upstream/6864; ENST00000587464/Downstream/6886;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/120891, chr19-CpG: 197/Downstream/24715
Upstream sequence
atagttggaagtaaagctctcctcagcaaatgtaaaagaacagaaattataacaaactatctctcagaccacagtgcaatcaaactagaactcaggatta
Downstream sequence
agaatctcactcaaagccactcaactacatggaaactgaacaacctgctcctgaatgactactgggtacataacgaaatgaaggcagaaataaagatgtt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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