Basic Information
VIS ID
TVIS10014263
Fusion event
HBV-LINC00636 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|middle S protein|
Start
114
Orient
+
Integrated sequence
CCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCC| |TTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTT
Host Sequence
Chromosome
chr3
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
107607029/107888182 (Hg38)
End
107607029/107888182 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00636
Nearest miRNA
hsa-let-7g/Upstream/4364066; hsa-mir-12124/Downstream/1714646;
Nearest TSS
ENST00000440867/Upstream/4934; ENST00000607746/Downstream/166557;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/362699, chr3-CpG: 46/Downstream/39441
Upstream sequence
ctgaggtctgatttaactttggtttggtattctatgatatctaacagttacagtctgatatctctttgttctcctctcctttccataggaaactggctgg
Downstream sequence
aagaacatctttatttctgccttcatttcgttatgtacccagtagtcattcaggagcaggttgttcagtttccatgtagttgagtggctttgagtgagat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate