STIM2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014283
Fusion event
HBV-STIM2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|middle S protein|
Start
11
Orient
+
Integrated sequence
AATTCCACAAC| |CTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCT
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
26926133/26924511 (Hg38)
End
26926133/26924511 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
STIM2
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-1185-1-3p ; hsa-mir-1185-2-3p
Nearest miRNA
hsa-mir-12113/Upstream/2404221; hsa-mir-1243/Downstream/1895071;
Nearest TSS
ENST00000502981/Upstream/63052; ENST00000477474/Downstream/78489;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/62895, chr4-CpG: 55/Downstream/3353588
Upstream sequence
gtatttgacttcaataacaaaccaaagaacaaaaattatgtaatcatctcaatagaggcagcaaagttatttggaaaaatcaaacatcaaacctgataaa
Downstream sequence
ggacacattcaaagcagtgtgtagagggaaatttatagcactaaatgcctacaagagaaagcaggaaagatccaaaattgacaccctaacatcacaatta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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