Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014300
Fusion event
HBV-MUSK integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
111
Orient
+
Integrated sequence
CTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCT| |CCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGT
Host Sequence
Chromosome
chr9
Cytoband
q31.3
Reference genome
End
113556040/110793760 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7a-1/Upstream/1282215; hsa-mir-12126/Downstream/477396;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/214011, chr9-CpG: 129/Downstream/243873
Upstream sequence
ttggtctgggcttttggtggaccattttaatcaaattacactgggaaattttcttgtttttttttttttgtccccttcaacttggattatatggatatga
Downstream sequence
tctctcagaccacagtgcaatcaaactagaactcaggattaagaatctcactcaaagccactcaactacatggaaactgaacaacctgctcctgaatgac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.