Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014315
Fusion event
HBV-CACNA1S integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2269
Orient
+
Integrated sequence
AACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCG| |GAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCC
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
End
201046055/201076927 (Hg38)
Orient
+
Location type
Exonic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/2217774; hsa-mir-1182/Downstream/642581;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/53056, chr1-CpG: 110/Downstream/37403
Upstream sequence
ctggagaaggtgatgcccaccttgatcttgaaggacaagaagcaggattcagcaaccgttcagaaggagggacacgcagagggagagcctacctggaaga
Downstream sequence
cgctgatgagggCTTGGGGAAAGTTGTCAAAGTTGCTGCGCCGTACTTCTGTGTCTTCAAAGTCATACCTCCCCCCAAAGAGCTGCATGCCCAGGAGGGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.