Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014316
Fusion event
HBV-CACNA1S integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1798
Orient
-
Integrated sequence
TGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTG| |GTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTG
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
End
201046072/201076944 (Hg38)
Orient
-
Location type
Exonic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/2217791; hsa-mir-1182/Downstream/642564;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/53073, chr1-CpG: 110/Downstream/37386
Upstream sequence
caccttgatcttgaaggacaagaagcaggattcagcaaccgttcagaaggagggacacgcagagggagagcctacctggaagacgctgatgagggCTTGG
Downstream sequence
GGAAAGTTGTCAAAGTTGCTGCGCCGTACTTCTGTGTCTTCAAAGTCATACCTCCCCCCAAAGAGCTGCATGCCCAGGAGGGCGAAGATGACGATGAAGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.