Basic Information
VIS ID
TVIS10014328
Fusion event
HBV-chr11 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
2106
Orient
+
Integrated sequence
AGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTA| |GCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGT
Host Sequence
Chromosome
chr11
Cytoband
q25
Reference genome
GRCh37/hg19
Start
134840214/134970320 (Hg38)
End
134840214/134970320 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7a-2/Upstream/1071739;
Nearest TSS
ENST00000527297/Upstream/19612; ENST00000532071/Downstream/105579;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/8051, None/Downstream
Nearby gene
LOC283177(-464659) ;
Upstream sequence
aagaaagtaaaaacactgacccacagaatgggaaaaatatttgcaaactgtaatctgaccagggtctagtataaagaataaagacgtcttacagctcaaa
Downstream sequence
cacgaaagggaaaatattccaattaaggtgaacaaagaatttaaataggcatctctcccggaactttatcaatggccaagaagcccatgaagagatgctc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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