VISDB Viral Integration Site DataBase

VIS ID

TVIS10014332

Fusion event

HBV-FAT3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1929

Orient

+

Integrated sequence

CCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT| |GGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAG

Chromosome

chr11

Cytoband

q14.3

Reference genome

Start

End

92063549/92330383 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-132-3p ; hsa-mir-19b-3p ; hsa-mir-16-5p ; hsa-mir-1303 ; hsa-mir-296-3p ; hsa-mir-6820-3p ; hsa-mir-3164 ; hsa-mir-4719 ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-32-3p ; hsa-mir-4747-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-7977 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4736 ; hsa-mir-3665 ; hsa-mir-383-3p ; hsa-mir-4717-5p ; hsa-mir-1295b-3p ; hsa-mir-1270 ; hsa-mir-1273e ; hsa-mir-3160-3p ; hsa-mir-3689d ; hsa-mir-4459 ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-4683 ; hsa-mir-5186 ; hsa-mir-558 ; hsa-mir-5694 ; hsa-mir-6134 ; hsa-mir-620 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6840-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-4662a-5p ; hsa-mir-4676-5p ; hsa-mir-4684-5p ; hsa-mir-548c-3p ; hsa-mir-575 ; hsa-mir-6771-3p ; hsa-mir-6858-3p

Nearest miRNA

hsa-mir-10392/Upstream/1461181; hsa-let-7a-2/Downstream/1403291;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/103517, chr11-CpG: 35/Downstream/536392

Nearby gene

MIR4490(-1774524) ; FAT3(+21713) ;

Upstream sequence

TTTGGCATTAATCCATGGAAGCTGCCCTATCCCCCTCTCTGCTTTATTCATGTCCTAACAGTTTGTCTGCCTGTTGGAGAATCTAGCAGAGCTATCTGTG

Downstream sequence

TGCCCTCTGCCTTTtaactctgagcaagacattttcattgtcttgtccttggcttcctcagcggtacaatgaaagATAGTTTATACGTTAAATTTCAGGA