Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014335
Fusion event
HBV-CEP290 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1799
Orient
-
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
Host Sequence
Chromosome
chr12
Cytoband
q21.32
Reference genome
Start
End
88479719/88085942 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7i/Upstream/1340793; hsa-mir-1178/Downstream/6475847;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/50113, chr12-CpG: 34/Downstream/56016
Upstream sequence
TTAAATAGTGAATTCAAATTAACTATATCTGCTGTTCATTATTGGCTATTAGAAACATTATAGGAGAATAGAAAAATAGTGAAATTAGCAATAGATTCAT
Downstream sequence
CATTCTATGCATTGCCCTCATAAAGAAATATTATTTAGAAAGCCCCCCAAACATACCAAATAATACACTAATCAAAATGCAAATTCTTCTAATTACCTCT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.