VISDB Viral Integration Site DataBase

VIS ID

TVIS10014337

Fusion event

HBV-INTS6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2222

Orient

+

Integrated sequence

TTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTG| |TCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTA

Chromosome

chr13

Cytoband

q14.3

Reference genome

Start

End

51979231/51405095 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-mir-192-3p ; hsa-mir-4662a-5p ; hsa-mir-616-3p ; hsa-mir-4317 ; hsa-mir-95-5p

Nearest miRNA

hsa-mir-15a/Upstream/56456; hsa-mir-1267/Downstream/147494;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/153187, chr13-CpG: 186/Downstream/46460

Nearest cancer related gene

INTS6(TSG, No orient, 0)

Upstream sequence

AAAAATATGCATAAAGTACAAAAGAATAAATGATTAGGGGACAAACcagggaagacttctcagaggaagtagcatctgagcaagtgtgaagaataaTAAG

Downstream sequence

TTTACTGAGAATCCAGAACCTCATGCAAGTTAGGGAGTAATGAAGAGTGAAGATCATGATCAAACACATAGGAGACAAGAAATAATAATAATAAATACTG