Basic Information
VIS ID
TVIS10014340
Fusion event
HBV-chr13 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1798
Orient
-
Integrated sequence
TGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTG| |GTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTG
Host Sequence
Chromosome
chr13
Cytoband
q21.32
Reference genome
End
66858474/66284342 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-1297/Upstream/66018; hsa-mir-1267/Downstream/11413670;
Nearby gene
PCDH9(+18492) ;
Nearest cancer related gene
PCDH9(TSG, +18492) ;
Upstream sequence
cttccaggttttacccactatccagttccaaatccacttgcacatttttaggtatttgttatggcaacctccccacctcttggtaccagtGTTCtgtctt
Downstream sequence
agtctgttttgtgctgctaaacaaaatacctgagactaggtattaataaaggaaaaaataattatcagagttctataggctgggaagtccaagttctgtg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate