VISDB Viral Integration Site DataBase

VIS ID

TVIS10014342

Fusion event

HBV-SAMD4A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1726

Orient

-

Integrated sequence

CGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTT| |AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT

Chromosome

chr14

Cytoband

q22.2

Reference genome

Start

End

55173992/54707274 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-548an ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-1911-3p ; hsa-mir-8485 ; hsa-mir-377-3p ; hsa-mir-1305 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-345-5p ; hsa-mir-4680-3p ; hsa-mir-5187-3p ; hsa-mir-4427 ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-4714-5p ; hsa-mir-556-3p ; hsa-mir-3140-3p ; hsa-mir-124-3p ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-6815-3p ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-3692-5p ; hsa-mir-93-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-3918 ; hsa-mir-3158-3p ; hsa-mir-6895-5p ; hsa-mir-379-3p ; hsa-mir-411-3p ; hsa-mir-6870-3p

Nearest miRNA

hsa-mir-208a/Upstream/758790; hsa-mir-1185-1/Downstream/170839;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/139162, chr14-CpG: 143/Downstream/194555

Upstream sequence

ctcacagcagcatcaacctcctggactcaagcaatcctcccacctcagcctcttgagtatctgggaccacaggcatgcaccaccacacccagataatttt

Downstream sequence

tgtattttttgtggagacagggtctccctgtgttgcccaggctggtctcaaactcctgggctcaaataatcctcctgcgtaagcctcccaaagtgctggg