VISDB Viral Integration Site DataBase

VIS ID

TVIS10014350

Fusion event

HBV-WDR72 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1824

Orient

-

Integrated sequence

TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAG

Chromosome

chr15

Cytoband

q21.3

Reference genome

Start

End

54001200/53709003 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-5590-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4719 ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-10393/Upstream/1431803; hsa-mir-11181/Downstream/1663937;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/902724, chr15-CpG: 33/Downstream/50455

Upstream sequence

CTCATGCAGCTGCTGGAAGGAAAGACGAATCCTCATTCTTACCACTGTAACTCCATCAGCAGATATGTACATGGGCATTACAAACAATAACTGAGAACCT

Downstream sequence

GTTACTGTCAAACCTGGAGATTTAATTCTATGGTATTACTCCAAAAAATGAGTTCAGACAATAGTACCTGCTTACAGAGCAGTCTTTTCTAAGCTCACTG